Which of the following is a major factor in determining the depth of a burn?

The depth of a burn is primarily influenced by the duration of contact between the skin and the source of the burn. The longer the exposure to a heat source, the deeper the burn can penetrate the skin layers. High temperatures can cause more severe damage quickly, but without prolonged contact, the burn may not reach deeper tissues. Thus, even if the temperature is very high, a brief exposure may result in a superficial burn rather than a deeper injury. By understanding this, responders can better assess burn injuries and determine the appropriate response and treatment for affected individuals.

While the location of the burn can affect its healing process and complications, and the age of the patient can influence the skin's vulnerability and healing capacity, the specific depth of the burn itself is mainly dictated by how long the skin is in contact with the heat source.